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2010 – Shi Zheng-Li, Wuhan bat virus researcher, got $7M National Institutes of Health (NIH) US taxpayer funding from Anthony Fauci for “gain-of-function”

Oct 16, 2014 – Obama stopped Fauci NIH funding of Shi and her collaborators at UNC and Harvard

July 23, 2015 – European Patent EP3172319 filed “Coronavirus” – issued to Pirbright Oct 18, 2019; Updated May 8, 2020 “strategically funded by… including Gates.”

Sept 21, 2015 – US Patent 9441041 – filed by Fauci et al.; Issued Sept 13, 2016. “Use of antagonists between HIV gp120 and .alpha.4.beta.7 Integrin.” 

Nov 9, 2015 – By using Vero E6 cell line that Shi obtained from Ft Detrick USAMRIID, Shi transformed the virus to seek humans.  Later this COVID-19 virus was found to have gp120 from HIV that causes immune system failure and is a critical target for vaccine development.

Jan 10, 2017 – Fauci said “THERE WILL BE A SURPRISE OUTBREAK”

Jan 20, 2017 – Trump inaugurated

Dec 2017 – NIH, on its own, resumed funding, sent total $5.96M through EcoHealth Alliance

Jan 28, 2020 – FBI arrested Lieber, chair of Harvard chemistry

Mid-March 2020 – Xinhua, the official Chinese news agency, wrote a People’s Republic of China official threatened that China might impose export controls to withhold antibiotics and other life-saving drugs from American consumers. Those controls, he stated, would plunge America “into the mighty sea of coronavirus.”

Mar 11, 2020 – World Health Organization declared pandemic

April 24, 2020 – President Trump forces NIH to cancel funding

May 26, 2020 – Shi warns coronavirus is just “tip of the iceberg.”

July 15, 2020 – Fauci said “This is a pandemic of historic proportions…. it’ll be comparable to what we saw in 1918.” (virtual Georgetown University forum)

Aug 29, 2020 – Fauci via NIH again gives $7.5 million to EcoHealth Alliance that funneled millions to Wuhan China virus lab. The first grant was finally stopped in April at the height of the pandemic. Now NIH re-funds them to resume similar research.







Lawrenceville, NJ (Dr Charles B. Simone) – I asked myself several questions:

WHY is the current COVID-19 coronavirus (SARS-Cov-2) so powerful, and so virulent?

WHY does it preferentially seek out people who have high ACE2 docking sites on their cells due to their prescription medicines or diseases, obesity, smoking?

WHY does it cause tremendous immune system dysfunction in many infected people, similar to what we see with AIDS patients?  A “cytokine storm” which is a surge of activated immune cells into the lungs resulting in more lung inflammation and fluid buildup that can lead to respiratory distress.

And Who funded this?



The current COVID-19 coronavirus (SARS-Cov-2) is virtually similar to the bat SARS-like coronavirus previously discovered by the Nanjing Military Research Command in 2018 – with 100% amino acid sequence of the viral surface proteins, nsp7 and E.  This 100% similarity indicates that it cannot be a natural mutation.

In fact, there are several insertions into the current virus that were put there on purpose:

1) S protein, also called the Spike protein, found on the COVID-19 (SARS-Cov-2) coronavirus is identical to the Spike protein found on the previous SARS virus. This Spike protein attaches to the ACE2 docking sites on human cells of the heart, respiratory tract, intestine, kidney, eye, and blood vessels.  The Spike protein allows the virus to invade the human cell. The Spike proteins of the natural strains do not infect human cells at all – this has all been published since 2007 from Wuhan University.  If this Spike protein were not on the new COVID-19 virus, it would be harmless to humans.

ACE2 sites are increased by : (DRUGS INCREASE RISK FOR SARS-CoV-2 (COVID-19) INFECTION https://bit.ly/2J1YJW6

Ibuprofen – taken by millions of Americans

Anti-hypertension medicines taken by tens of millions of Americans

ACE (angiotensin-converting enzyme) inhibitors

ARBs (angiotensin II type-I receptor blockers)

Thiazolidinediones (used to treat diabetes)

Diabetes – 34 million Americans

Obesity / Overweight – 169 million Americans

Having COPD – 16 million Americans

Smoking – 34 million Americans

Immunocompromised – 10 million Americans

 2) The insertion of gp120-gp41 from the HIV virus  – results in immune system failure 




Shi Zheng-Li, Virologist at Wuhan Institute of Virology, bat researcher.  Source: Times of India

2003 to 2010Shi Zheng-Li, a virologist at the Wuhan Institute of Virology P4 lab, discovered that the spike protein was the key for the bat coronavirus to invade the human.  Shi also discovered that the SARS virus was made by rearranging several SARS-like bat coronaviruses.

August 22, 2005 – “Chloroquine is a potent inhibitor of SARS coronavirus infection and spread.” Virol J. 2005 Aug 22;2:69. This paper is from the Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.

June 2010Shi altered several key amino acid residues of the virus to enhance the ability of the Spike protein to easily attach to the ACE2 receptor, thus allowing for an easy invasion of the human.

https://www.ncbi.nlm.nih.gov/pubmed/20567988 Angiotensin-converting enzyme 2 (ACE2) proteins of different bat species confer variable susceptibility to SARS-Co-V entry. Arch Virol 2010. 155:1563-69.

2010 – FUNDING – Dr Anthony Fauci, Director of the National Institutes of Allergy and Infectious Diseases (NIAID), promoted the work of Dr Shi Zheng-Li and gave Shi more than $7 million of U.S. taxpayer money for bat viruses “gain-of-function” research (Newsweek) – research that increases the virulence and ease of spread or host range of dangerous pathogens.

$3.7 million was given to Shi for the first phase of the two-part funding by the NIAID, NIH. 

Shi’s proposal stated: “We will use S protein (spike protein) sequence data, infectious clone technology, in vitro and in vivo infection experiments and analysis of receptor binding to test the hypothesis that % divergence thresholds in S protein sequences predict spillover potential.” Spillover potential means that the virus can go directly from an animal to a human because of the Spike protein that attaches to the ACE2 receptor on human cells of the respiratory tract, intestine, kidney, eyes, and blood vessels.


December 30, 2011 – in the Washington Post Drs. Fauci, Nabel, and Collins defended this type of work, “[D]etermining the molecular Achilles’ heel of these viruses can allow scientists to identify novel antiviral drug targets that could be used to prevent infection in those at risk or to better treat those who become infected. Decades of experience tells us that disseminating information gained through biomedical research to legitimate scientists and health officials provides a critical foundation for generating appropriate countermeasures and, ultimately, protecting the public health.”

A flu virus risk worth taking.https://www.washingtonpost.com/opinions/a-flu-virus-risk-worth-taking/2011/12/30/gIQAM9sNRP_story.htmlGary Nabel, director of the Vaccine Research Center at the National Institute of Allergy and Infectious Diseases; Francis Collins, director of the National Institutes of Health.

However, more than 200 scientists wanted the research stopped because a pandemic could occur.

May 2013 (submitted) – October 2013 (published) – Shi found one bat SARS-like virus had the Spike protein that attached to the ACE2 receptors of human cells.

https://www.nature.com/articles/nature12711 Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor. Nature 503, 535–538 (2013). https://doi.org/10.1038/nature12711


October 16, 2014  – the Obama Administration forced the National of Institutes of Health to stop these studies, suspending 21 studies that included “gain-of-function” – research that increases the virulence and ease of spread or host range of dangerous pathogens. This included Shi Zengh-Li’s research her collaborators, Dr Ralph Baric, and others at the University of North Carolina, as well as multiple researchers at Harvard.

July 23, 2015 – European Patent EP3172319 “CORONAVIRUSFiled; Issued To Pirbright Institute on Oct 18, 2019; Updated May 8, 2020. “The Institute is strategically funded by…. including the Bill & Melinda Gates Foundation” – statement by Pirbright | Ash Road, Woking, Surrey GU24 0NF / GB |


Sept 21, 2015US Patent Number: 9441041, Filed by Anthony Fauci et al; Issued September 13, 2016. “Use of antagonists between HIV GP120 and .alpha.4.beta.7 Integrin.”


November 9, 2015IMPORTANT PAPER Shi Zheng-Li made a synthetic virus by inserting the Spike protein from her work published in 2013 into the backbone of the SARS bat virus.  This new intentionally made chimeric virus can directly and easily attach, invade and infect human cells.  To accomplish this transformation Shi Zheng-Li used the Vero E6 cell line obtained from Fort Detrick Army Research Institute of Infectious Diseases (USAMRIID) Bio Safety Lab, Level 4.

https://www.nature.com/articles/nm.3985 A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence. 2015 Dec;21(12):1508-13. doi: 10.1038/nm.3985. Epub 2015 Nov 9. 
Please note the names of the authors and their affiliations: Vineet D Menachery¹, Boyd L Yount Jr², Kari Debbink¹ ², Sudhakar Agnihothram³, Lisa E Gralinski¹, Jessica A Plante¹, Rachel L Graham¹, Trevor Scobey¹, Xing-Yi Ge4, Eric F Donaldson¹, Scott H Randell 5,6, Antonio Lanzavecchia 7, Wayne A Marasco 8,9, Zhengli-Li Shi 4 & Ralph S Baric¹ ²
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. 2 Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. 3 National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas, USA. 4 Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China. 5 Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. 6 Cystic Fibrosis Center, Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. 7 Institute for Research in Biomedicine, Bellinzona Institute of Microbiology, Zurich, Switzerland. 8 Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA. 9 Department of Medicine, Harvard Medical
The Vero E6 cell line was originally isolated from the kidney of a normal adult African green monkey on March 27, 1962 at the Chiba University in Chiba, Japan. It was brought to the National Institute of Allergy and Infectious Diseases at the National Institutes of Health in the United States, and was provided to the American Type Culture Collection (ATCC) in 1966.

Shi considered research on primates to determine what effect it would have on humans.

November 12, 2015 – Nature News – article entitled Engineered bat virus stirs debate over risky research. “If the virus escaped nobody can predict the trajectory.”

January 10, 2017Anthony Fauci MD, Director of National Institutes of Allergy and Infectious Diseases, at a black tie event at Georgetown University said, “There is no question that there will be a challenge the coming administration in the area of infectious diseases, both chronic infectious diseases in the sense of already ongoing disease…but also there will be a surprise outbreak.

https://youtu.be/59a0uGIFZGY at time marker 3:40

January 20, 2017Donald Trump inaugurated as the 45th President of the United States.


November 2017 report by ,EcoHealth Alliance‘s project published in Virologica Sinica warned that “some bat SARSr-CoVs [severe acute respiratory syndrome-related coronaviruses] are able to directly infect humans without intermediate host.”  EcoHealth Alliance obtained NIH funds to then fund Shi’s research at the Wuhan University.

December 2017the NIH, on its own, ended the moratorium and began the second phase of the NIAID project that included the gain-of-function research.

This was done without informing the Trump Administration as might be expected to be done since the Obama Administration placed a moratorium on this research. The review process for this research was done in secrecy.


The second phase, close to $4 million U.S. taxpayer money, included gain-of-function research to see how the bat virus could attack humans via genetic engineering.  The project was run by EcoHealth Alliance, a non-profit research group, headed by President Peter Daszak.  Since 2008 EcoHealth Alliance has received $5.96 million NIH funding for this work.

https://taggs.hhs.gov/Detail/AwardDetail?arg_AwardNum=R01AI079231&arg_ProgOfficeCode=104    https://taggs.hhs.gov/Detail/AwardDetail?arg_AwardNum=R01AI110964&arg_ProgOfficeCode=104

November 14, 2018Shi Zheng-Li gave a talk at the School of Life Sciences and Biotechnology entitled Studies on Bat Coronavirus and It’s Cross Species Infection.


October 7 to October 24, 2019 – Emergency shutdown of Wuhan Institute of Virology “suggesting hazardous event”based on no mobile phone activity.

January 21, 2020China’s President Xi Jinping asked World Health Organization to withhold information on transmission and delay pandemic warning. 

January 28, 2020FBI arrested Charles Lieber, chairman of Harvard’s chemistry department. He was working for the Wuhan Institute of Technology of China and received $50,000 per month plus living expenses and grant money. He participated in the Chinese program called the Thousand Talents Plan organized to attract American experts to disclose intellectual property and technology. “All of the individuals charged today were either directly or indirectly working for the Chinese government at our country’s expense,” said FBI Special Agent in Charge Joseph Bonavolonta.

February 2, 2020the spike glycoprotein120 (gp120) sequence and 3 other new sequences were found inserted into the COVID-19 (SARS-Cov-2) virus. The same four sequences are found in HIV virus (GenBank), and the bat coronavirus discovered by Shi.  Three molecules of gp120 are linked together and anchored to the membrane by the gp41 protein.  This gp120-gp41 complex facilitates entry and together cause human immune system failure.The spike gp120 is a critical target for vaccine development.

https://www.biorxiv.org/content/10.1101/2020.01.30.927871v1.full#T1  Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag.  https://pubmed.ncbi.nlm.nih.gov/20088758/ The gp120 Molecule of HIV-1 and Its Interaction With T Cells

February 25, 2020National Center for Medical Intelligence warned that the coronavirus would become a pandemic within 30 days – WATCHCON 1 an imminent crisis. This group is located in Ft Detrick in Frederick MD.

Mid-March 2020 – Xinhua, the official Chinese news agency, wrote a People’s Republic of China official threatened that China might impose export controls to withhold antibiotics and other life-saving drugs from American consumers. Those controls, he stated, would plunge America “into the mighty sea of coronavirus.”


March 11, 2020 – World Health Organization declared pandemic.


April 24, 2020 – President Trump forces NIH to cancel funding.

May 26, 2020 – China’s bat woman researcher warned coronavirus is just “tip of the iceberg” (New York Post)

July 15, 2020 – Fauci said “This is a pandemic of historic proportions…. it’ll be comparable to what we saw in 1918.” (virtual Georgetown University forum).

Aug 29, 2020 – Fauci via NIH again gives $7.5 million to EcoHealth Alliance that funneled millions to Wuhan China virus lab. The first grant was finally stopped in April at the height of the pandemic. Now NIH re-funds them to resume similar research.  https://www.npr.org/sections/goatsandsoda/2020/08/29/907237520/group-whose-nih-grant-for-virus-research-was-revoked-just-got-a-new-grant

Oct 12, 2020 – World Health Organization does not advocate lockdowns.  Researchers at Stanford and other medical groups agree.


COVID-19 (SARS-Cov-2) is a new intentionally made chimera virus that can directly and easily attach, invade and infect humans, especially those who have a great many ACE2 receptors due to prescription medications, ibuprofen, diabetes, obesity, COPD, smoking, and immunocompromise.

This virus will remain in the virus pool of infectious agents.



1) Determine who and what institutions have subscriptions to the journals in which Shi Zheng-Li has published those articles above.

2) Hold the Chinese Communist Party and China accountable for lives lost and economic losses via the U.S. and international banking system.  Revoke all properties bought by Chinese companies/nationals that are vital to the U.S. Stop all  people and Chinese imports that may pose a risk to the U.S.  Boycott Chinese products, including food products.  The U.S. Food and Drug Administration must rigorously ensure that all food products that originate from any foreign country must be labeled as such and not permit phrases like “assembled” or “distributed by an ABC Company, USA” without denoting the country of origin.

3) Hold accountable and charge Shi Zheng-Li and all collaborators and funders of Shi Zheng-Li’s work as well as people and organizations that deceived the world: including, but not limited to individuals, Institutes, universities, countries, political parties and organizations, companies, institutions, organizations, et al.  These crimes include but are not limited to: treason, terrorism, murder, psychological warfare, family dysfunction, suicide, early death and morbidity from undiagnosed or progressive diseases since patients could not follow up, economic losses at all levels, and crimes against humanity.  

4) Repeal the 1980 Bayh-Dole Act that allows federally funded scientists to patent their findings.  These patents belong to the U.S. taxpayer.  By repealing the Act it would also eliminate Other Transaction Agreement (OTA) that prevents the government from being able to use march-in rights that normally allows the government to ensure taxpayer-funded products can be accessed at a reasonable price.

5) Repeal the 1986 National Vaccine Injury Compensation Act that currently protects Big Pharma by eliminating all liabilities from their vaccines.

6) Investigate holders of all coronavirus and/or HIV patents that may pertain to this pandemic and who benefits from these patents.  Here are some:

US Patent 20060257852  Severe acute respiratory syndrome coronavirus
Filed April 6, 2004  — Granted Nov 16, 2006
Assigned to Chiron  — Sold to GlaxoSmithKline
Inventors Rappuoli; Rino; (Castelnuovo Berardenga, IT) ; Masignani; Vega; (Siena, IT) ; Stadler; Konrad; (Scharnstein, AU) ; Gregersen; Jens Peter; (Wetter, DE) ; Chien; David; (Alamo, CA) ; Han; Jang; (Lafayette, CA) ; Polo; John M.; (Danville, CA) ; Weiner; Amy; (Fairfield, CA) ; Houghton; Michael; (Danville, CA) ; Song; Hyun Chul; (Berkeley, CA) ; Seo; Mi-Young; (Yongin-si, KR) ; Donnelly; John; (Moraga, CA) ; Klenk; Hans Dieter; (Marburg, DE) ; Valiante; Nicholas; (Fremont, CA)
European Patent EP3172319 CORONAVIRUS
Filed July 23, 2015  –  Issued To Pirbright Institute on Oct 18, 2019; Updated May 8, 2020

“The Institute is strategically funded by the Biotechnology and Biological Sciences Research Council, part of UK Research and Innovation (BBSRC UKRI) and also receives funding from many other organisations including the Bill & Melinda Gates Foundation” – statement by Pirbright | Ash Road, Woking, Surrey GU24 0NF / GB |

Anthony S. Fauci MD patents – The spike glycoprotein 120 (gp120) is a critical target for vaccine development for COVID-19 (SARS-Cov-2).  https://patents.justia.com/inventor/anthony-s-fauci

7) Stop undergraduate and graduate school admissions to foreigners from countries that are not American allies. Defensive/vital U.S. companies must stop hiring Chinese nationals. In June 2017 President Xi enacted the Chinese National Intelligence Law that gives authorities powers to monitor and investigate foreign and domestic individuals and institutions. It allows Chinese intelligence agencies to search premises, seize property, and mobilize individuals or organizations to carry out espionage. It also gives intelligence agencies legal ground to carry out their work both in and outside China. 

8) Stop funding all research in foreign countries that are not American allies, especially gain-of-function research and any other research that could potentially harm the United States of America. Instead, fund the many young American research investigators who are not funded.

9) Decrease risks (Simone Ten Point Plan) and maintain good blood pressure and diabetes control.  More than half of the American population have risk factors and / or take medicines that increase the ACE2 receptor that allows this virus to attach and infect human cells.  Once these patients are infected, it may be too late.  Therefore, physicians should consider substituting ACE inhibitors or ARBs primarily with vasodilating beta blockers (carvedilol, labetalol, nebivolol), and, if more blood pressure control is needed, then add calcium channel blockers.   Also, consider substituting thiazolidinediones with other diabetes medicines to maintain blood glucose control.

10) As Shi Zheng-Li’s papers were published and the alarming results evolved, why have we not been warned and protected years ago by the National Institutes of Health, virologists, infectious disease experts, the Center for Disease Control and Prevention, National Center for Medical Intelligence, US Army Research Institute of Infectious Diseases (USAMRIID), Defense Intelligence Agency, the Central Intelligence Agency, the Federal Bureau of Investigation, Homeland Security, the National Security Agency, State Department, FEMA, military and other intelligence agencies, and others?

© 2020 Charles B. Simone, M.MS., M.D.