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Lawrenceville, NJ (Dr. Simone) – Vitamin B3, also known as Niacin has three chemical forms. The Nicotinic Acid form of Niacin lowers cholesterol, lowers LDL, lowers triglycerides, lowers lipoprotein (a), and raises HDL. Nicotinic acid also can clean out the arterial walls from all the cholesterol accumulation. One rarely hears about this because there is no patent on vitamins and hence no “drug” status possible for a pharmaceutical company. The words Nicotinic Acid must be on the label.
Nicotinic acid can cause “flushing” and “pins and needles” sensation. So, you have to gradually increase the dose from 250 mg to ultimately 1500 mg. 1500 mg per day is the minimum dose necessary to begin positively changing your lipids.
Start with 250 mg tablet with the large dinner meal. Never buy “No Flush” and never buy “Timed Release” or “Delayed Release” or “Inositol” or “Niacinamide.” Some of these cause liver damage and have no effect on your lipids.
Food will minimize the reaction. Aspirin 325 mg will minimize the reaction. Simone Super Energy will also minimize the reaction.
Then every three to four days, increase the dose by another 250 mg per day. The body will become accustomed to it and you will have only a very minimal reaction. The goal will be to take about 1000 mg at dinner with aspirin, another 250 mg at breakfast and another 250 mg at lunch.
In about 6 weeks after you attain the 1500 mg dose per day your lipids will improve. Make sure your physician is directly overseeing your progress because you will need blood work to check your blood sugar, complete blood counts, including platelet count. A meta-analysis of 11 randomized trials involving 26,340 nondiabetic patients showed that during a follow-up of 3.6 years, there was a 34% higher risk of diabetes (Goldie et al. Heart. 2016; 102:198-203).
Nicotinic acid (a form of niacin) and Aspirin are two relatively safe, easily available and inexpensive drugs known to significantly reduce the levels of lipoprotein (a).
Nicotinic acid may not be appropriate for some people with gout, diabetes, stomach ulcer, glaucoma, clotting disorder (decreases fibrinogen and therefore decreases clotting), liver disease, or alcoholism.
(c) 2015 Charles B Simone, M.MS., M.D.