PATHWAYS TO THROMBOSIS DURING INITIAL AND RECURRENT INFECTIONS LIKE COVID AND THERAPEUTIC PLASMA EXCHANGE (TPE)
Recurrent deep venous thrombosis (DVT) during infectious diseases like COVID-19 happens because the virus triggers a severe systemic inflammatory and procoagulant state. [1, 2]
The mechanisms driving this increased risk are explained through Virchow’s triad (endothelial injury, hypercoagulability, and stasis) combined with specific immune responses: [1, 2]
1. Endothelial Injury and Viral Direct Invasion
2. Hypercoagulability (Overactive Clotting)
3. Venous Stasis
