by Dr Simone | Apr 27, 2026 | Dr Simone, Healthcare Costs, HEALTHCARE CRISIS, PSYCHEDELICS
Psychedelic-assisted therapies, including psilocybin- and MDMA-based interventions, demonstrate promising but preliminary efficacy for certain psychiatric conditions, particularly treatment-resistant depression and post-traumatic stress disorder. However, the current evidence base is derived predominantly from small, highly controlled clinical trials with carefully selected participants, intensive therapeutic support, and methodological limitations (including challenges with blinding and expectancy effects).
Until such evidence is established, first-line treatment should remain evidence-based pharmacotherapy and psychotherapy with well-characterized efficacy and safety profiles.
by Dr Simone | Apr 22, 2026 | ANTICOMPETITIVE MERGERS, Big Pharma, Dr Simone, Healthcare Costs, HEALTHCARE CRISIS
U.S. antitrust policy should be strengthened to address anticompetitive mergers in the pharmaceutical sector, particularly “killer acquisitions” that eliminate emerging competition. This includes lowering reporting thresholds in highly concentrated health care markets, requiring the inclusion of intangible assets such as patents in merger evaluations, and applying heightened scrutiny to transactions involving overlapping products. Regulators, including the Federal Trade Commission and the Department of Justice, should also require enforceable commitments to continued product development and post-merger transparency. These reforms would help preserve competition, promote innovation, and protect patients from high prices and reduced access to essential therapies.
by Dr Simone | Apr 2, 2026 | ACE2, Big Pharma, Bioweapon, CDC, CORONAVIRUS, COVID-19, Dr Simone, FDA, HEALTHCARE CRISIS, VACCINE
The Coronavirus and mRNA patents and medical papers evolved from 1989 onward. In 1999 Bill Gates had to re-brand himself and started Global Alliance for Vaccines and Immunization to market vaccines.
In Feb 2011, he “specifically requested” Epstein’s help. Epstein created a pre-COVID operational structure — financialized, globally coordinated, and partially integrated with Pentagon biodefense systems — that he built, staffed, and rehearsed. Epstein put himself at the junction of these systems, linking philanthropic capital, Wall Street finance, global health governance, and Pentagon biosecurity research.
by Dr Simone | Mar 12, 2026 | “Shared clinical decision-making”, Advisory Committee on Immunization Practices, CDC, Dr Simone, FDA, Healthcare, HEALTHCARE CRISIS, mRNA COVID shot, The Simone Report
In principle, shared clinical decision-making aims to make care more individualized and collaborative. In practice, however, it can place complex judgments about uncertain evidence into the hands of patients who may have limited time, information, or technical expertise to fully evaluate the choices.
by Dr Simone | Nov 15, 2025 | Health Policy, Healthcare, HEALTHCARE CORPORATIZATION, Healthcare Costs, HEALTHCARE CRISIS, The Simone Report
Big investors are buying hospitals, nursing homes, and doctor’s practices. This can bring money and technology—but often puts profits over patients.
Costs up, quality down: Private equity nursing homes have worse staffing and outcomes. Hospital mergers drive prices up.
Doctors under pressure: Loopholes let corporations control practices behind the scenes.
Solutions: Transparency on ownership, quality standards, smarter Medicare/Medicaid rules, and stronger oversight.
by Dr Simone | Dec 22, 2024 | Antioxidants, Cancer, Cancer and Nutrition, Health Policy, Healthcare, Healthcare Costs, HEALTHCARE CRISIS, Inflammation, Linus Pauling PhD, VITAMINS
VITAMIN C PLUS CHEMOTHERAPY DOUBLES SURVIVAL in METASTATIC PANCREATIC CANCER
